question on 6 month post TX

Question:

In article <14406-43B40443…@storefull-3256.bay.webtv.net>, elmoemer…@webtv.net says… – Hide quoted text — Show quoted text ->Re: question on 6 month post TX   >Group: alt.support.hepatitis-c Date: Thu, Dec 29, 2005, 9:22am From: >HangininTh…@verizon.com (Frank) >In article <1135863974.603396.264…@f14g2000cwb.googlegroups.com>, >Chill…@rogers.com says… >Hi Everyone. I was at my appt. yesterday and I had a question for the >hep nurse. I am not sure I got a straight answer. I know I will get one >here. How many people tested negative for the virus from week 12, 24, 48 >to have the virus come back to life 6 months past the treatment. >According to my BCLD, about 25% show no response after 12 weeks and are >temporarily taken off medication. >I asked her this question because as you know I am in a study and the >nurse told me that everyone is responding to treatment but none have >completed the program. If everyone is responding to treatment then who >are the 40 percent who don’t? >Mags >thanks for the spellchecker link! >You can show SVR after 48 weeks but 6 months thereafter, test positive >again for HCV. That is the 40% they’re speaking of, mags. >//////////// >Sorry, Frank, but you’re incorrect.  The 40% I believe Mags is referring >to are the 40% that don’t achieve SVR with the current tx with Peg and >riba.  If you’re undetectable by 12 weeks, I think the SVR rate becomes >near 90%. >elmo  

I stand corrected. Thanks elmo.

Response:

In article <14406-43B40443…@storefull-3256.bay.webtv.net>, – Hide quoted text — Show quoted text - elmoemer…@webtv.net wrote: > Re: question on 6 month post TX   > Group: alt.support.hepatitis-c Date: Thu, Dec 29, 2005, 9:22am From: > HangininTh…@verizon.com (Frank) > In article <1135863974.603396.264…@f14g2000cwb.googlegroups.com>, > Chill…@rogers.com says… > Hi Everyone. I was at my appt. yesterday and I had a question for the > hep nurse. I am not sure I got a straight answer. I know I will get one > here. How many people tested negative for the virus from week 12, 24, 48 > to have the virus come back to life 6 months past the treatment. > According to my BCLD, about 25% show no response after 12 weeks and are > temporarily taken off medication. > I asked her this question because as you know I am in a study and the > nurse told me that everyone is responding to treatment but none have > completed the program. If everyone is responding to treatment then who > are the 40 percent who don’t? > Mags > thanks for the spellchecker link! > You can show SVR after 48 weeks but 6 months thereafter, test positive > again for HCV. That is the 40% they’re speaking of, mags. > //////////// > Sorry, Frank, but you’re incorrect.  The 40% I believe Mags is referring > to are the 40% that don’t achieve SVR with the current tx with Peg and > riba.  If you’re undetectable by 12 weeks, I think the SVR rate becomes > near 90%. > elmo  

Here: http://www.hivandhepatitis.com/2005icr/easl/docs/041805_b.html Using Peg-IFN and Riba, in a study of non-responders and relapsers, 61% of that group who had a viral load of 0 at week 12 achieved SVR.  That number is higher for people who were on their first round of treatment. Elmo – the 90% figure maybe comes from the number for people who don’t respond at 12 weeks, it’s 98% chance of the the treatment _not_ working. G

Response:

> In article <1135863974.603396.264…@f14g2000cwb.googlegroups.com>, > Chill…@rogers.com says…

[..] > >I asked her this question because as you know I am in a study and the > >nurse told me that everyone is responding to treatment but none have > >completed the program.  If everyone is responding to treatment then who > >are the 40 percent who don’t?

You’re on a new drug, no?   If everyone is responding to treatment early on then that – with the old drugs – is associated with a higher rate of SVR. What they hope is that the SVR rate with the new drug will be at least as good if not better based on the same early response. It’s as good as the news you could have at this point could be, I think. G

Response:

Re: question on 6 month post TX   Group: alt.support.hepatitis-c Date: Thu, Dec 29, 2005, 10:02am From: HangininTh…@verizon.com (Frank) In article <14406-43B40443…@storefull-3256.bay.webtv.net>, elmoemer…@webtv.net says… Re: question on 6 month post TX Group: alt.support.hepatitis-c Date: Thu, Dec 29, 2005, 9:22am From: HangininTh…@verizon.com (Frank) In article <1135863974.603396.264…@f14g2000cwb.googlegroups.com>, Chill…@rogers.com says… Hi Everyone. I was at my appt. yesterday and I had a question for the hep nurse. I am not sure I got a straight answer. I know I will get one here. How many people tested negative for the virus from week 12, 24, 48 to have the virus come back to life 6 months past the treatment. According to my BCLD, about 25% show no response after 12 weeks and are temporarily taken off medication. I asked her this question because as you know I am in a study and the nurse told me that everyone is responding to treatment but none have completed the program. If everyone is responding to treatment then who are the 40 percent who don’t? Mags thanks for the spellchecker link! You can show SVR after 48 weeks but 6 months thereafter, test positive again for HCV. That is the 40% they’re speaking of, mags. //////////// Sorry, Frank, but you’re incorrect. The 40% I believe Mags is referring to are the 40% that don’t achieve SVR with the current tx with Peg and riba. If you’re undetectable by 12 weeks, I think the SVR rate becomes near 90%. elmo I stand corrected. Thanks elmo. /////// yep!  Now let’s get back to crepitating.  :-) elmo http://community.webtv.net/elmoemerson/DocElmosHepFile http://community.webtv.net/elmoemerson/TheFamilyAlbum

Response:

In article <14405-43B40B2E…@storefull-3256.bay.webtv.net>, elmoemer…@webtv.net says… – Hide quoted text — Show quoted text ->Re: question on 6 month post TX   >Group: alt.support.hepatitis-c Date: Thu, Dec 29, 2005, 10:02am From: >HangininTh…@verizon.com (Frank) >In article <14406-43B40443…@storefull-3256.bay.webtv.net>, >elmoemer…@webtv.net says… >Re: question on 6 month post TX >Group: alt.support.hepatitis-c Date: Thu, Dec 29, 2005, 9:22am From: >HangininTh…@verizon.com (Frank) >In article <1135863974.603396.264…@f14g2000cwb.googlegroups.com>, >Chill…@rogers.com says… >Hi Everyone. I was at my appt. yesterday and I had a question for the >hep nurse. I am not sure I got a straight answer. I know I will get one >here. How many people tested negative for the virus from week 12, 24, 48 >to have the virus come back to life 6 months past the treatment. >According to my BCLD, about 25% show no response after 12 weeks and are >temporarily taken off medication. >I asked her this question because as you know I am in a study and the >nurse told me that everyone is responding to treatment but none have >completed the program. If everyone is responding to treatment then who >are the 40 percent who don’t? >Mags >thanks for the spellchecker link! >You can show SVR after 48 weeks but 6 months thereafter, test positive >again for HCV. That is the 40% they’re speaking of, mags. >//////////// >Sorry, Frank, but you’re incorrect. The 40% I believe Mags is referring >to are the 40% that don’t achieve SVR with the current tx with Peg and >riba. If you’re undetectable by 12 weeks, I think the SVR rate becomes >near 90%. >elmo >I stand corrected. Thanks elmo. >/////// >yep!  Now let’s get back to crepitating.  :-) >elmo

I farted and it popped like Bazooka bubble gum.  Does that count.   ;}

Response:

Re: question on 6 month post TX   Group: alt.support.hepatitis-c Date: Thu, Dec 29, 2005, 4:20pm (CST+6) From: ga_mondra…@yahoo.com (Gordo

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